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To design a clinically translatable nanomedicine for photodynamic theranostics, the ingredients should be carefully considered. A high content of nanocarriers may cause extra toxicity in metabolism, and multiple theranostic agents would complicate the preparation process. These issues would be of less concern if the nanocarrier itself has most of the theranostic functions. In this work, a poly(ethylene...
In article number 1806444, Zhong‐Xing Jiang, Peng Huang, and co‐workers synthesize an amphiphile to emulsify perfluorohexane into a nanoemulsion for multimodal‐imaging‐guided photodynamic therapy. The rupture of the nanoemulsion in tumor tissues can render opposite changes of the photoacoustic and fluorescence/magnetic resonance signals of the amphiphile. Furthermore, the inner perfluorohexane can...
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