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Epidemiologists are often interested in estimating the effect of functions of time‐varying exposure histories in relation to continuous outcomes, for example, cognitive function. However, the individual exposure measurements that constitute the history upon which an exposure history function is constructed are usually mismeasured. To obtain unbiased estimates of the effects for mismeasured functions...
Purpose
To demonstrate the feasibility of 129Xe MR in evaluating the pulmonary physiological changes caused by PM2.5 in animal models.
Methods
Six rats were treated with PM2.5 solution (16.2 mg/kg) by intratracheal instillation twice a week for 4 weeks, and another six rats treated with normal saline served as the control cohort. Pulmonary function tests, hyperpolarized 129Xe multi‐b diffusion‐weighted...
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