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The effects of different dietary ratios of polyunsaturated fatty acids (PUFAs) and monounsaturated fatty acids (MUFAs) to saturated fatty acids (SFAs) [(PUFA+MUFA)/SFA] on plasma and hepatic lipids, the activities of hepatic regulatory enzymes of cholesterol metabolism, and low-density lipoprotein (LDL) uptake of hepatocytes and Kupffer cells were examined. In this study, 2 different types of diets...
To determine whether high polyunsaturated and monounsaturated fatty acid to saturated fatty acid [(P+M)/S] ratio in diets increases plasma lipoprotein lipids and reduces the hepatic hypertriglyceridemic effect of dietary cholesterol, we compared plasma lipoproteins and liver lipids in 64 rats. Rats were fed diets with the same polyunsaturated fatty acids/saturated fatty acids (P/S) ratio of 1.0, but...
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