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Vaccine design ushered in the era of nanotechnology, as the vaccine is being developed toward particulate formulation. We have previously shown that the attenuated pneumolysin mutant (ΔA146PLY) was a safe and effective pneumococcal vaccine candidate. Here, to further optimize the formulation, we fused calcium phosphate (CaP) binding domains with ΔA146PLY so that the biocompatible CaP can mineralize...
Catalytic dechlorination of para-nitrochlorobenzene (p-NCB) by Ni/Fe (nickel/iron) bimetallic nanoparticles was carried out. The catalytic reduction and dechlorination reaction was believed to take place on the surface site of the nanoscale catalysts. In the reaction, Ni plays a role of catalyst decreasing activation energy of hydrogenolysis of C–Cl bonds and the Fe was corroded to produce hydrogen...
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