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BackgroundThe vitreous has been shown to induce epithelial‐mesenchymal transdifferentiation because it induces fibroblast‐like morphology, enhanced migration and invasion in retinal pigment epithelial cells in proliferative vitreoretinopathy. Rac1 is the principal mediator of cell migration. In the current study, the relationship between Rac1 and cell migration, and invasion in vitreous‐transformed...
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