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MMP‐9 participates in tumour growth, invasion, metastasis and vascularisation. Thus, inhibition of MMP‐9 may be involved in the process of tumourigenesis. We have investigated the effect of RNAi‐mediated MMP‐9 silencing on inhibiting invasion and migration of mouse melanoma cell B16. A specific and optimised siRNA vector was used to target MMP‐9 mRNA synthesis in B16 cells. Changes of invasion and...
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