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ObjectivesTo identify the prognostic implications of human papillomavirus (HPV)‐related cell cycle marker profiles in patients who have received a transoral lateral oropharyngectomy (TLO) as a primary treatment for tonsillar squamous cell carcinoma (TSCC).
Patients and MethodsImmunohistochemical profiles of HPV‐related cell cycle markers, including p16, pRb, cyclin D1, p53, and the HPV DNA status...
BackgroundHuman papillomavirus (HPV)‐related oropharyngeal squamous cell carcinoma (SCC) exhibits distinct patterns worldwide, but its prevalence has not been extensively evaluated in Korea. The E7 oncogene‐mediated carcinogenesis and its meaning are yet to be uncovered for oropharyngeal SCCs.
MethodsIn a Korean oropharyngeal SCC cohort, epidemiological indicators, HPV, and G1 cell cycle marker expressions...
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