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Transmembrane signaling mechanisms are critical for regulating the plasticity of neuronal connections underlying the establishment of long‐lasting memory (e.g., Linden and Routtenberg (1989) Brain Res Rev 14:279–296; Sossin (1996) Trends Neurosci 19:215–218; Mayr and Montminy (2001) Nat Rev Mol Cell Biol 2:599–609; Chen et al. (2011) Nature 469:491–497). One signaling mechanism that has received surprisingly...
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