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Transient receptor potential melastatin 2 (TRPM2) assembles into tetramers to function as an oxidative stress‐sensitive Ca2+ channel at the surface membrane. Limited information is currently available on the 10 protein isoforms of mouse TRPM2 (mTRPM2) identified. This study investigated whether these isoforms function as Ca2+ channels and examined their effects on full‐length mTRPM2 activity using...
Current guidelines recommend endoscopic management (EM) for patients with low‐risk upper urinary tract urothelial carcinoma, as well as those with an imperative indication. However, regardless of the tumor risk, radical nephroureterectomy is still mainly performed worldwide despite the benefits of EM, such as renal function maintenance, no hemodialysis requirement, and treatment cost reduction. This...