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The cytoplasmic linker protein (CLIP)-170 localizes to kinetochores and is suggested to function in stable attachment of kinetochores to microtubule ends. Here we show that defects in kinetochore–microtubule attachment and chromosome alignment in CLIP-170-depleted cells were rescued by co-depletion of p150glued, a dynactin subunit required for kinetochore localization of CLIP-170. CLIP-170 recruited...
The cytoplasmic linker protein (CLIP)‐170 localizes to kinetochores and is suggested to function in stable attachment of kinetochores to microtubule ends. Here we show that defects in kinetochore–microtubule attachment and chromosome alignment in CLIP‐170‐depleted cells were rescued by co‐depletion of p150glued, a dynactin subunit required for kinetochore localization of CLIP‐170. CLIP‐170 recruited...
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