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ObjectivesIncreasing numbers of reports have described hematopoietic improvement after iron chelation therapy in iron‐overloaded patients. These observations indicate that excess iron could affect hematopoiesis unfavorably. To investigate how excess iron affects hematopoiesis in vivo, we generated iron‐overloaded mice and examined hematopoietic parameters in these mice.
MethodsWe generated iron‐overloaded...
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