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We studied changes in the quantity of reactive oxygen species (ROS) and the changes in mitochondrial morphology in cultured murine dermal fibroblast-like (MDF) cells from SAMP11 and SAMR1 mice. The quantity of ROS in the SAMP11 cells was greater than that in the SAMR1 cells after the 7th day in culture. We measured the enzymatic activity and mRNA quantity of the antioxidant enzymes (AOEs), but no...
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