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Différents mécanismes physiopathologiques ont été décrits dans la phénylcétonurie (PCU) mais les conséquences métaboliques indirectes des concentrations élevées de phénylalanine (Phe) et tyrosine (Tyr) restent partiellement inconnues. Nous avons utilisé une approche métabolomique multimodale pour évaluer la signature métabolique associée aux concentrations de Phe et de Tyr.Nous avons prospectivement...
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