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Overexpression or mutation of α‐synuclein (α‐Syn), a protein associated with presynaptic vesicles, causes familial forms of Parkinson's disease in humans and is also associated with sporadic forms of the disease. We used in vivo microdialysis, tissue content analysis, behavioral assessment, and whole‐cell patch clamp recordings from striatal medium‐sized spiny neurons (MSSNs) in slices to examine...
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