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Objective
Periostin is important for the maintenance of periodontal tissue, but its role in periodontitis is controversial. This research investigated the effect of periostin in periodontitis and the underlying mechanism.
Design
Mouse periodontitis models in vivo and inflammation model in vitro which were induced by Porphyromonas gingivalis lipopolysaccharide were established to evaluate periostin...
Objectives
This study aimed to clarify the regulatory role of Th17‐Treg balance in periodontitis and further reveal Treg plasticity.
Materials and Methods
An experimental periodontitis model was established by ligation and injection of Pg‐LPS. Inflammatory factors were measured by ELISA and RT‐PCR. Alveolar bone absorption was evaluated by micro‐CT and histomorphology. Quantities of Treg and Th17...
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