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Radiotherapy, a widely used therapeutic strategy for esophageal squamous cell carcinoma (ESCC), is always limited by radioresistance of tumor tissues and side‐effects on normal tissues. Herein, a signature based on four core genes of cyclic GMP‐AMP synthase‐stimulator of interferon genes (cGAS‐STING) pathway, is developed to predict prognosis and assess immune cell infiltration, indicating that the...
Radiotherapy Adjuvant
In article number 2311291, Yuliang Zhao, Zhihua Liu, Chunying Chen, and co‐workers report that a novel lipid‐modified manganese diselenide nanoparticle (MnSe2‐lipid) with extraordinarily uniform sphere morphology and tumor microenvironment responsiveness is developed. The released Mn2+ promotes radiosensitivity by generating reactive oxygen species induced by Fenton‐like reaction...