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Objective To determine the association between pancreatic cancer and medical conditions. Methods A large population-based case–control study identified pancreatic cancer cases in the San Francisco Bay Area between 1995 and 1999. A total of 1,701 controls were randomly selected from the same population and were frequency-matched to 532 cases by sex and age. In-person interviews were conducted with...
Treatment of pancreatic cancer remains a challenging task that often requires a multidisciplinary approach to confer optimal response and, ideally, maximize survival. A combination of locoregional approaches such as surgery and radiotherapy, along with systemic therapies for eradication of micrometastases, should be considered both for patients who are operative candidates and for those with locally...
Pancreatic adenocarcinoma is typically diagnosed at an advanced stage, at which point systemic therapy becomes the primary modality of treatment. Although gemcitabine monotherapy has remained the standard of care for the past decade, a number of large studies conducted over the past several years have suggested that some advantages may be derived from the use of combination therapy, such as the addition...
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