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Hepatocellular carcinoma (HCC), a prototype of hypervascular tumors, is one of the most common malignancies in the world, especially hyperendemic in the Far East where chronic hepatitis B virus (HBV) infection is highly prevalent. It is characterized by the clinical feature of a poor prognosis or a high mortality due to its already far advanced stages at diagnosis. It is so multifactorial that hepatocarcinogenesis...
Backgrounds/AimsMetastatic tumour antigen 1 (MTA1) promotes angiogenesis by stabilizing hypoxia‐inducible factor‐1α (HIF‐1α), which is closely associated with frequent postoperative recurrence and poor survival in patients with HCC. In this study, we determined single nucleotide polymorphisms (SNPs) in angiogenesis‐related genes that are associated with MTA1 overexpression in HCC tissues.
MethodsA...
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