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To assess patient response rates to medical therapies used to treat endometriosis-associated pain.A systematic review with the use of Medline and Embase.Not applicable.Women receiving medical therapy to treat endometriosis.None.The proportions of patients who: experienced no reduction in endometriosis-associated pain symptoms; had pain symptoms remaining at the end of the treatment period; had pain...
Pain is the central symptom in endometriosis and often persists despite treatment of the disease. Multiple mechanisms underlie endometriosis-associated pain including nociception, inflammation, and alterations in peripheral and central nervous system pain processing. As also occuring in other chronic conditions, pain in endometriosis is often associated with psychological distress and fatigue, both...
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