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Endothelin-1 (ET-1) and Endothelin-3 (ET-3) increased the expression of intercellular adhesion molecule-1 (ICAM-1) on rat neonatal cultured cardiac myocytes and rat aortic endothelial cells. ET-1-induced ICAM-1 expression on cardiac myocytes was inhibited by a selective ET A receptor antagonist, S-0139, but not by a selective ET B receptor antagonist, BQ788. ET-3-induced ICAM-1 expression...
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