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An efficient l-proline-accelerated synthesis of 9-substituted-2,3,4,9-tetrahydro-1H-xanthen-1-one derivatives has been accomplished via one-pot condensation of dimedone or 1,3-cyclohexanedione with substituted salicylaldehydes under mild reaction conditions. This protocol demonstrates several notable advantages, including operational simplicity, short reaction times, environmentally friendly conditions,...
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