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In biomedical research and practice, continuous biomarkers are often used for diagnosis and prognosis, with a cut‐point being established on the measurement to aid binary classification. When survival time is examined for the purposes of disease prognostication and is found to be related to the baseline measure of a biomarker, employing a single cut‐point on the biomarker may not be very informative...
In biomedical research and practice, quantitative tests or biomarkers are often used for diagnostic or screening purposes, with a cut point established on the quantitative measurement to aid binary classification. This paper introduces an alternative to the traditional methods based on the Youden index and the closest‐to‐(0, 1) criterion for threshold selection. A concordance probability evaluating...
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