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A rapid and sensitive method was developed and validated for the quantitative determination of xanthopurpurin (XPP) in rat plasma using ultra‐performance liquid chromatography‐electrospray ionization‐Orbitrap mass spectrometry. XPP inhibits IgE production and prevents peanut‐induced anaphylaxis. The XPP and emodin (internal standard) were determined in negative ion mode with m/z 239.0350 → 211.0400...
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