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To conduct a comprehensive quantitative proteomics analysis of novel serum protein biomarkers based on synovitis status associated with matrix metalloproteinase-3 (MMP-3) and to determine the clinical significance of these biomarkers in rheumatoid arthritis (RA).Patients with untreated RA (n=28), primary Sjogren’s syndrome (pSS) (n=30), and healthy controls (HCs) (n=30) were enrolled for the screening...
Background In this study, we sought to identify definitive biomarkers associated with disease activity in primary Sjögren’s syndrome (pSS). Methods Serum protein concentrations in pSS patients and healthy controls (HCs) were comprehensively screened using high-throughput proteomic analysis, and differentially expressed proteins were extracted. Correlation between differentially expressed proteins...
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