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Background & Aims
Short telomeres and genetic telomerase defects are risk factors for some human liver diseases, ranging from non‐alcoholic fatty liver disease and non‐alcoholic steatohepatitis to cirrhosis. In murine models, telomere dysfunction has been shown to metabolically compromise hematopoietic cells, liver and heart via the activation of the p53‐PGC axis.
Methods
Tert‐ and Terc‐deficient...
Background & AimsEmerging studies have focused the association between non‐alcoholic fatty liver disease (NAFLD) and the risk of type 2 diabetes mellitus (T2DM) but the results were inconsistent. In addition, few studies have put focus on the association between NAFLD and the risk of prediabetes. We aimed to investigate whether NAFLD diagnosed by ultrasonography could predict the risk of future...
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