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Spinal cord injury (SCI) involves complex pathological process which can be complicated by secondary injury. TREK‐1 is a member of the two‐pore domain potassium (K2P) channel family, which can be modulated by a number of physiological and pathological stimuli. Recent studies suggest that TREK‐1 plays an active role in depression, pain and neuroprotection. However, its role in the pathological process...
Multiple players are involved in motor and sensory dysfunctions after spinal cord injury (SCI). Therefore, therapeutic approaches targeting these various players in the damage cascade hold considerable promise for the treatment of traumatic spinal cord injury. Soluble epoxide hydrolase (sEH) is an endogenous key enzyme in the metabolic conversion and degradation of P450 eicosanoids called epoxyeicosatrienoic...
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