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Background
Individuals with colorectal polypectomy are recommended to undergo surveillance colonoscopies at certain intervals to prevent subsequent colorectal cancer. Use of postpolypectomy surveillance according to the 2006 US Multi‐Society Task Force (USMSTF) recommendations in an integrated health care system was investigated.
Methods
Use of surveillance colonoscopies was prospectively assessed...
BACKGROUND
To date, no targeted therapy has been approved for nasopharyngeal carcinoma (NPC), and this underscores the need for an in‐depth understanding of clinically relevant genomic alterations (CRGAs).
METHODS
Comprehensive genomic profiling was performed for 190 NPC patients, including 20 patients with nasopharyngeal adenocarcinoma (NPAC), 62 patients with nasopharyngeal squamous cell carcinoma...
BACKGROUND
Biliary tract cancers (BTCs) typically present at an advanced stage, and systemic chemotherapy is often of limited benefit.
METHODS
Hybrid capture–based comprehensive genomic profiling (CGP) was performed for 412 intrahepatic cholangiocarcinomas (IHCCAs), 57 extrahepatic cholangiocarcinomas (EHCCAs), and 85 gallbladder carcinomas (GBCAs). The mutational profile was correlated with the...
BACKGROUNDIn the current study, the authors present a comprehensive genomic profile (CGP)‐based study of advanced urothelial carcinoma (UC) designed to detect clinically relevant genomic alterations (CRGAs).
METHODSDNA was extracted from 40 µm of formalin‐fixed, paraffin‐embedded sections from 295 consecutive cases of recurrent/metastatic UC. CGP was performed on hybridization‐captured, adaptor ligation‐based...
BACKGROUNDThe authors hypothesized that comprehensive genomic profiling of advanced‐stage cutaneous squamous cell carcinoma (cSCC) could identify genomic‐derived drug targets of therapy for patients with conventional therapy‐resistant disease.
METHODSComprehensive genomic profiling of 315 cancer genes was applied to 50 ng of DNA from 122 cSCC cases for the evaluation of all classes of genomic alterations...
Lung cancer is the leading cause of cancer‐related death worldwide. In China, the incidence of lung cancer has grown rapidly, resulting in a large social and economic burden. Several researchers have devoted their studies to lung cancer and have demonstrated that there are many risk factors for lung cancer in China, including tobacco use, environmental pollution, food, genetics, and chronic obstructive...
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