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Oxygen Reduction Reaction
In article number 2305062, Tianyu Xia, Han Gao, Haizhong Guo, and co‐workers develop the quasi‐octahedral core‐shell electrocatalyst with L10‐PtCo as the core and ultrathin, strained PtIr layer as the shell. It delivers impressive activity and durability in the oxygen reduction reaction (ORR). In the dual catalysis of ORR and oxygen evolution reaction, a small overpotential...
PtIr‐based nanostructures are fascinating materials for application in bifunctional oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) catalysis. However, the fabrication of PtIr nanocatalysts with clear geometric features and structural configurations, which are crucial for enhancing the bifunctionality, remains challenging. Herein, PtCo@PtIr nanoparticles are precisely designed...
Developing nanomedicines with superior reactive oxygen species (ROS) scavenging capability has emerged as a promising strategy in treating ROS‐related diseases, for example, drug‐induced liver injury. However, designing nanoscavengers with the self‐propelling ability to scavenge ROS actively remains challenging. Here, a self‐propelled silica‐supported ultrasmall gold nanoparticles‐tannic acid hybrid...
Photothermal‐Gas Synergistic Cancer Therapy
In article number 2206749, Benhui Hu, Yun Liu, and co‐workers propose a cascade reaction‐promoted CO release strategy to realize augmented photothermal‐gas synergistic cancer therapy. Gold‐based porphyrinic coordination polymer nanosheets synthesized by a simple aqueous phase reaction, with ultrasmall zero‐valent gold as the coordination node, have the advantages...
As a gasotransmitter, carbon monoxide (CO) possesses antitumor activity by reversing the Warburg effect at higher concentrations. The targeted delivery of carbon monoxide‐releasing molecules (CORMs) using nanomaterials is an appealing option for CO administration, but how to maintain CO above the threshold concentration in tumor tissue remains a challenge. Herein, a nanozyme‐catalyzed cascade reaction...
Nanoparticles (NPs) have attracted tremendous interest in drug delivery in the past decades. Microfluidics offers a promising strategy for making NPs for drug delivery due to its capability in precisely controlling NP properties. The recent success of mRNA vaccines using microfluidics represents a big milestone for microfluidic NPs for pharmaceutical applications, and its rapid scaling up demonstrates...
Dimensional engineering of perovskite solar cells has attracted significant research attention recently because of the potential to improve both device performance and stability. Here, a novel 2D passivation scheme for 3D perovskite solar cells is demonstrated using a mixed cation composition of 2D perovskite based on two different isomers of butylammonium iodide. The dual‐cation 2D perovskite outperforms...
Exosomes are endosome‐derived vesicles enriched in body fluids such as urine, blood, and saliva. So far, they have been recognized as potential biomarkers for cancer diagnostics. However, the present single‐variate analysis of exosomes has greatly limited the accuracy and specificity of diagnoses. Besides, most diagnostic approaches focus on bulk analysis using lots of exosomes and tend to be less...
Durability is still one of the key obstacles for the further development of photocatalytic energy‐conversion systems, especially low‐dimensional ones. Encouragingly, recent studies show that nanoinsulators such as SiO2 and MgO exhibit substantially enhanced photocatalytic durability than the typical semiconductor p25 TiO2. Extending this knowledge, MgO–Au plasmonic defect nanosystems are developed...
Solution‐processed semiconductor single‐crystal patterns possess unique advantages of large scale and low cost, leading to potential applications toward high‐performance optoelectronic devices. To integrate organic semiconductor micro/nanostructures into devices, various patterning techniques have been developed. However, previous patterning techniques suffer from trade‐offs between precision, scalability,...
Many nanomaterials are reported to disrupt lysosomal function and homeostasis, but how cells sense and then respond to nanomaterial‐elicited lysosome stress is poorly understood. Nucleus translocation of transcription factor EB (TFEB) plays critical roles in lysosome biogenesis following lysosome stress induced by starvation. The authors previously reported massive cellular vacuolization, along with...
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