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Toll‐like receptor 7 (TLR7) triggers antiviral immune responses through its capacity to recognize single‐stranded RNA. TLR7 loss‐of‐function mutants are associated with life‐threatening pneumonia in severe COVID‐19 patients. Whereas TLR7‐driven innate induction of type I IFN appears central to control SARS‐CoV2 virus spreading during the first days of infection, the impact of TLR7‐deficiency on adaptive...
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