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Staphylococcus aureus is a gram-positive pathogen responsible for a wide variety of diseases. RNAIII is the key effector of the accessory gene regulator (agr) system. It is a regulatory RNA (514 nucleotides long) that acts at both transcription and translation level to regulate the production of numerous toxins, enzymes and cell surface proteins. Here, we reveal that map (major histocompatibility...
SsrA RNA (small stable RNA A), also known as tmRNA and 10Sa RNA, functions both as tRNA and mRNA through its unique structure. The carotenoid pigment is the eponymous feature of human pathogen Staphylococcus aureus. Here, we found that the pigment of the mutant strain with ssrA deletion was increased. Furthermore, it was demonstrated that ssrA could act as an antisense RNA aside from its well-known...
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