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Aims
Gastric neuroendocrine carcinoma (NEC) is a rare and aggressive subtype with a poor prognosis. We aim to investigate expression profiles of HER2 and programmed death ligand 1 (PD‐L1) in gastric NEC to test the potential applicability of drugs targeting these molecules.
Methods and results
Expression levels of HER2 and PD‐L1 were evaluated in 25 gastric NECs, including 10 pure NECs and 15 mixed...
Estimation of the cancer cell fraction in breast cancer tissue is important for exclusion of samples unsuitable for multigene prognostic assays and a variety of molecular analyses for research. Here, we aimed to establish a breast cancer cell fraction marker based on DNA methylation. First, we screened genes unmethylated in non-cancerous mammary tissues and methylated in breast cancer tissues using...
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