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Objective
This study aimed to assess the association between adipose tissue distribution and severity of clinical course in patients with severe acute respiratory syndrome coronavirus 2.
Methods
For this retrospective study, 143 hospitalized patients with confirmed coronavirus disease 2019 (COVID‐19) who underwent an unenhanced abdominal computed tomography (CT) scan between January 1, 2020, and...
Objective
To determine the relationship of the gain‐of‐function variant A750T in leucine‐rich repeat containing G protein‐coupled receptor 4 (LGR4) with central obesity and related metabolic phenotypes.
Methods
The LGR4 A750T (c.2248 G > A) variant was detected by Sanger sequencing in a discovery young population and a validation community‐based population with obesity from eastern China. Fat...
ObjectiveTo clarify the quantitative relationship of body mass index (BMI) change from early adulthood to midlife with presence of type 2 diabetes mellitus (T2DM) after midlife.
MethodsThis study included 120,666 middle‐aged and elderly, whose retrospectively self‐reported body weight at 20 and 40 years and measured height were available. BMI at 20 and 40 years and BMI change in between were defined...
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