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In the field of ophthalmology, postoperative endophthalmitis (POE) is a serious surgical complication, which may lead to poor visual outcome even after the infection has been controlled. In the study, we develop a sustained drug releasing system loaded with levofloxacin which is expected to be effective against common pathogens responsible for POE for at least 7 days after single application at the...
In this study, a novel chitosan adsorbent (CS-MEIC) modified by imidazolium-based ionic liquid was prepared for the efficient adsorption of Re(VII). The results indicated that CS-MEIC could obtain higher uptake capacity for Re(VII) when the volume ratio of N-methyl imidazole to epichlorohydrin was 1:2, and the mass of the CS was 0.3 g. The adsorption process was described best by Langmuir monolayer...
Amoxicillin is a traditional antibiotic used to treat Helicobacter pylori (H. pylori). However, the clinical applicability was limited by low local concentrations of amoxicillin that are reached at the sites of H. pylori infection. In this study, a pH-sensitive, guanidine-containing polypeptide composed of poly(γ-glutamic acid) (γ-PGA) and arginine (Arg) were synthesized. The γ-PGA-g-Arg polypeptide...
Calcium phosphate cement (CPC) composite by the incorporation of chitosan fiber (CF) and gelatin was investigated for flexural strength, phase composition, microstructure, and in vitro cellular response. The results demonstrated that the incorporation improved the flexural strength significantly (maximum, 12.31 MPa), together with accelerating the conversion of CPC components to hydroxyapatite (HA)...
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