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We characterized the uniformity and sensitivity of the distributed feedback laser biosensors in 96-well microplate format, with a thickness standard deviation of ∼35 nm. An assay was also used to demonstrate its biomolecule detection ability.
Photonic crystal enhanced fluorescence (PCEF) has been demonstrated as an effective technique for amplifying the electromagnetic excitation and emission extraction from surface-bound fluorescent molecules. Although optimal coupling of a fluorophore-exciting light source to the PC occurs with the use of collimated plane waves, PCEF surfaces are also capable of coupling light from focused sources but...
A wide variety of optical resonator structures have been used for label-free detection of chemical compounds, biomolecules, and cells, and several approaches have been developed commercially for application in life science research, environmental monitoring, quality control testing, and diagnostic testing. Label-free resonant optical sensors generally detect shifts in resonant wavelength or coupling...
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