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Autophagy
To overcome the autophagy compromised mechanism of protective cellular processes by “eating” damaged organelles or potentially toxic materials in tumor cells, Nan Li and co‐workers show how tellurium double‐headed nanobullets (TeDNBs)‐HO is utilized to induce autophagy dysfunction. On the one hand, TeDNBs‐mediated endoplasmic reticulum stress could excessively induce autophagy; thus, resulting...
To overcome the autophagy compromised mechanism of protective cellular processes by “eating”/“digesting” damaged organelles or potentially toxic materials with autolysosomes in tumor cells, lysosomal impairment can be utilized as a traditional autophagy dysfunction route for tumor therapy; however, this conventional one‐way autophagy dysfunction approach is always limited by the therapeutic efficacy...
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