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Acetaminophen (APAP), one of the most widely used antipyretics and analgesics, principally results in acute liver injury (ALI) in developed countries when taken overdose. Ferulic acid (FA) is a natural polyphenol compound existing in many plants that has free radical scavenging, anti‐inflammatory, and liver‐protective properties. However, the effect and underlying mechanism of FA in treating APAP‐induced...
In vivo mineralization is a multistep process involving mineral‐protein complexes and various metastable compounds in vertebrates. In this complex process, the minerals produced in the mitochondrial matrix play a critical role in initiating extracellular mineralization. However, the functional mechanisms of the mitochondrial minerals are still a mystery. Herein, an in vitro enzymatic reaction strategy...
In article number 1804321, Ying‐Jie Zhu, Zheng‐Dong Cai, Feng Chen, and co‐workers report an enzymatic reaction strategy for the generation of biomimic nanominerals. The results provide in vitro evidence for the effect of ATP on the formation and stabilization of the biomineral, and demonstrate a potential strategy for the preparation of the biomimic mineral for treating bone related diseases.
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