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The photosensitized generation of reactive oxygen species, and particularly of singlet oxygen [O2(a1Δg)], is the essence of photodynamic action exploited in photodynamic therapy. The ability to switch singlet oxygen generation on/off would be highly valuable, especially when it is linked to a cancer‐related cellular parameter. Building on recent findings related to intersystem crossing efficiency,...
Orthogonale Bodipy‐Dimere haben großes Potential als aktivierbare Photosensibilisatoren in der photodynamischen Therapie. In ihrer Zuschrift auf Seite 5430 ff. beschreiben J. Yoon, E. U. Akkaya et al. einen solchen Photosensibilisator, der durch eine Reaktion mit Glutathion (GSH) aktiviert wird. Vergleichende Zellkulturstudien belegen, dass der Photosensibilisator bevorzugt in Krebszellen eingeschaltet...
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