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Time-of-flight (TOF) data can improve the imaging quality of positron emission tomography (PET) cameras by estimating the location of the positron annihilation. In this study, we measured the TOF resolution of lutetium yttrium orthosilicate (LYSO) blocks based on the photomultiplier-quadrant-sharing (PQS) design, which has no external light guide and therefore has higher light collection efficiency...
In the front-end circuit of a Positron Emission Tomography (PET) camera, adjusting the photomultipliers (PMT) gain by changing the voltage distribution in dynodes instead of changing the total high voltage is more convenient to realize, and this method is better in signal-to-noise-ratio (SNR) than using a variable-gain-amplifier (VGA) in the signal path which may induce extra noise. In this study,...
We developed and built a solid LYSO detector ring for a new MD Anderson Murine PET (MUPET) camera using regular Ø 19 mm photomultipliers in quadrant-sharing (PQS) configuration. 180 PQS pentagon blocks distributed in 6 sub-rings (30 blocks each) constitute the detector system Each block has nominal dimensions of 19 ×x 19 × 10 mm3 in a 13 × 13 crystal array. To form a zero gap solid ring, PQS-blocks...
Current clinical PET with 4-6 mm intrinsic resolution (6-9 mm practical) limits many important brain studies. The objective of this study is to use our existing technology for realizing an ultrahigh resolution high-sensitivity PET with a lower cost for neuroimaging. This proposed neuro-PET has a 54-cm detector ring diameter, a large 21-cm axial field of view (AFOV) for capturing the whole brain and...
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