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Ytterbium(III) and praseodymium(III) complexes of 2-carboxyethylgermanium sesquioxide (Ge-132) can hydrolyze the phosphodiester linkage of 3 ,5 -cyclic adenosine monophosphate (cAMP) and 3 ,5 -cyclic deoxyadenosine monophosphate (dcAMP). Both cAMP and dcAMP are hydrolyzed with high selectivity, yielding predominantly 3 -monophosphates. The selectivity and activity for hydrolyzing cAMP and dcAMP...
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