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We entered the 10th Annual PhysioNet/Computers in Cardiology Challenge to predict which intensive care patients would experience an acute hypotensive episode (AHE) using physiologic data prior to the occurrence of the AHE. An AHE was defined through mean arterial blood pressure (ABP). We took a pragmatic approach to the Challenge. We explored six basic indices derived from ABP data near the forecast...
Reduction in mean arterial pressure (MAP) is a late indictor of progressive circulatory pathology. Non-invasive monitoring methods that are superior indicators of circulatory compromise would be clinically valuable. With IRB approval, 21 healthy volunteers were subjected to progressive lower body negative pressure (LBNP) until the onset of presyncopal symptoms. We evaluated the usefulness of four...
We have recently introduced a unique technique to automatically estimate both cardiac output (CO) and left atrial pressure (LAP) by pulmonary artery pressure (PAP) waveform analysis. In this contribution, we review the technique and present its evaluation with respect to gold standard, but highly invasive, reference aortic flow probe CO and direct LAP catheter measurements from two dogs during various...
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