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Ultrasound enhances the rate of reductive cleavage of the C 6 -oxygen bond of sesquiterpene enonelactones. trans-Eudesmanolides 1c-1g, cis-eudesmanolides 2a-2c, and trans-guaianolides 4a-4d react with Zn in acetic acid-H 2 O under sonochemical conditions to afford the corresponding sesquiterpene acids 3a-3g and 5a-5d, respectively in good yields. Starting from 5d two natural guaianes...
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