The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Copper‐amyloid peptides are proposed to be the cause of Alzheimer’s disease, presumably by oxidative stress. However, mice do not produce amyloid plaques and thus do not suffer from Alzheimer’s disease. Although much effort has been focused on the structural characterization of the copper‐ human amyloid peptides, little is known regarding the copper‐binding mode in murine amyloid peptides. Thus, we...
Die Koordinationsweise des Kupfer(II)‐Ions in CuII‐Aβ(1–16) beim physiologischen pH‐Wert wurde durch ENDOR‐Spektroskopie (34 GHz) charakterisiert. Die Messungen mit 1H/2H‐, 14N‐, 17O‐ und 1H‐ENDOR ergaben, dass der NH2‐Rest von Asparaginsäure als äquatorialer Ligand an CuII gebunden ist, während ein Wassermolekül axial koordiniert (siehe Bild; Cu rosa, O rot, N blau).
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.