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Co‐delivery of both chemotherapy drugs and siRNA from a single delivery vehicle can have a significant impact on cancer therapy. In article number 1700743, Jennifer Cha and co‐workers demonstrate that significant amounts of DNA can be encapsulated within poly(lactic‐co‐glycolic acid) (PLGA)‐containing nanoparticles through the use of a new synthetic DNA analog, click nucleic acids (CNAs), demonstrating...
Co‐delivery of both chemotherapy drugs and siRNA from a single delivery vehicle can have a significant impact on cancer therapy due to the potential for overcoming issues such as drug resistance. However, the inherent chemical differences between charged nucleic acids and hydrophobic drugs have hindered entrapment of both components within a single carrier. While poly(ethylene glycol)‐block‐poly(lactic‐...
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