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Cell lysis is an important and crucial step for the detection of intracellular secrets. Usually, cell lysis is based on strong ultrasonic waves or toxic chemical regents, which require a large amount of cell suspension. To obtain high efficiency cell lysis for a small amount of sample, a mechanical cell lysis method based on a surface acoustic wave (SAW) microchip is proposed. The microchip simply...
In article number 1804593, Zhaoxin Geng, Hong Liu, and co‐workers introduce a cell lysis method in a surface acoustic wave (SAW) microchip. When a biofluid droplet containing cells and microparticles is dropped on the working microchip, the cell membrane function is disrupted by the SAW. The intracellular contents are released after cell lysis, which can be used in disease diagnosis and stem cell...
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