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Naturally occurring melanin‐based nanoparticles (MNPs) are developed as a highly efficient and biocompatible nanoplatform for drug delivery for cancer imaging‐guided treatment. Specifically the FDA‐approved drug Sorafenib, which has high hydrophobicity, is successfully loaded into MNPs to prepare a water‐soluble nanocomplex for positron emission tomography (PET) and photoacoustic‐imaging‐guided tumor...
In order to promote imaging‐guided chemotherapy for preclinical and clinical applications, endogenous nanosystems with both contrast and drug‐delivery properties are highly desired. Here, the simple use of melanin is first reported, and this biopolymer with good biocompatibility and biodegradability, binding ability to drugs and ions, and intrinsic photoacoustic properties, can serve as an efficient...
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