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Scope: Theaflavin‐2 (TF‐2), a major component of black tea extract, induces apoptosis of human colon cancer cells and suppresses serum‐induced cyclooxygenase‐2 (COX‐2) expression 1. Here, we explored the mechanisms for activation of apoptosis, evaluated the impact on inflammatory genes in a broader panel of cells and tested whether topical anti‐inflammatory effects could be observed in vivo.
Methods and results:...
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