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Myocardial infarction, among other ischemic heart diseases, is the major cause of mortality and morbidity for patients who have heart diseases. Timely reperfusion of the ischemic myocardium is the most effective way to treat myocardial infarction. However, blood reperfusion to the ischemic tissues leads to an overproduction of toxic reactive oxygen species (ROS), which can further exacerbate myocardial...
In article number 2004377, Ke Cheng, Xiaojie Wang, and co‐workers fabricate a fibroblast growth factor (FGF)‐loaded and reactive oxygen species (ROS)‐responsive hydrogel for intrapericardial delivery. The safety and feasibility of minimally invasive injection and access into the pericardial cavity in both pigs and human patients are also demonstrated.
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