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Background and Aim
The inflammasomes promote pro‐caspase‐1 cleavage, leading to processing of pro‐interleukin (IL)‐1β into its mature form. We investigated the role of the IL‐1β and nucleotide binding oligomerization domain‐like receptor protein 3 (NLRP3) inflammasome in gastric injury in mice receiving water‐immersion restraint stress (WIRS), focusing on the cyclooxygenase (COX)‐2/prostaglandin...
Sonoda R, Naomoto Y, Shirakawa Y, Fujiwara Y, Yamatsuji T, Noma K, Tanabe S, Takaoka M, Gunduz M, Tsujigiwa H, Nagatsuka H, Ohara N, Yoshino T, Takubo K, Vieth M & Tanaka N (2010) Histopathology57, 90–100 Preferential up‐regulation of heparanase and cyclooxygenase‐2 in carcinogenesis of Barrett’s oesophagus and intestinal‐type gastric carcinomaAims: Metaplastic changes secondary to chronic...
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