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BackgroundWe investigated the feasibility of reirradiation with intensity‐modulated radiotherapy (IMRT) for recurrent T1 to T2 nasopharyngeal carcinoma (NPC) by assessing long‐term survival and late complication rates.
MethodsSixty patients who had been previously irradiated were diagnosed with locally recurrent T1 to T2 NPC and underwent reirradiation with IMRT. Severe radiation toxicities were...
Introduction The properties of a tumor itself were considered the main factors determining the survival of patients with locally recurrent nasopharyngeal carcinoma (NPC) treated with intensity-modulated radiotherapy (IMRT). However, recurrent tumors were mainly evaluated by using the American Joint Committee on Cancer staging system, which was modeled on primary tumors and did not incorporate the...
BACKGROUNDThe optimal model of total dose and fraction size for patients with locally recurrent nasopharyngeal carcinoma treated with intensity‐modulated radiotherapy (IMRT) remains unclear. The authors designed a randomized phase 2 clinical trial to investigate the efficacy of 2 different models, with the objective of determining an optimal model.
METHODSBetween January 2003 and December 2007, a...
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