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BACKGROUNDProstate cancer cells must maintain or achieve the further ability of proliferation during the progression. The molecular mechanisms, however, remain poorly understood. We identified a novel oncogene, termed membrane‐spanning 4‐domains, subfamily A, member 8B (MS4A8B), over‐expressed in prostate cancer.
METHODSWe firstly detected MS4A8B mRNA in 13 types of paired human normal and cancer...
BACKGROUNDProstate cancer is the third most common cancer and the second leading cause of cancer death for males in US. Livin has recently been described as a cancer‐associated member of inhibitor of apoptosis proteins family, highly expressed in prostate cancer. Livin gene encodes two splicing variants, termed Livin‐α and Livin‐β. We hypothesized that deregulation of proliferation could be due in...
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